Wuxi Further Pharmaceutical Co.,Ltd.
Add: Huishan Life Science and Technology Industrial Park, Huishan District, Wuxi, China
Whatsapp: + 86 18036885286; Email: wuxifurther@gmail.com
Lenmeldy——The most expensive drug in the word at present
Worldwide, the therapeutics market is already flooded with therapies that cost more than $1 million per dose. At least 10 drugs (As following table ) have reached this milestone, mainly gene therapies, but also small molecule drug modalities. Recently, the one-time gene therapy Lenmeldy for early-onset metachromatic leukodystrophy (MLD) of Orchard Therapeutics has been approved by the FDA for sale, priced at $4.25 million, raising the price of the world's most expensive drug by 21%.
| Drug name | Price/Dose（Million $） | Indications | Manufacturers | Approval time | Therapy Methods | |
| Lenmeldy | 4.25 | Metachromatic Leukodystrophy(MLD) | Orchard Therapeutics | 2024.3.18 | Gene therapy | |
| Hemgenix | 3.50 | Hemophilia B | CSL Behring and uniQure | 2022.11.22 | Gene therapy | |
| Skysona | 3.00 | CALD | Bluebird Bio | 2022.9.18 | Gene therapy | |
| Zynteglo | 2.80 | βThalassemia | Bluebird Bio | 2022.8.17 | Gene therapy | |
| Zolgensma | 2.10 | SMA | Nuohua | 2019.5.26 | Gene therapy | |
| Lamzede | 1.46 | Alpha-mannoside storage syndrome | Chiesi | 2023.2.16 | Enzyme replacement therapy | |
| Myalept | 1.26 | Systemic lipodystrophy | Chiesi Farmaceutici | 2014.2.25 | Protein | |
| Sohonos | 1.40 | FOP | Ipsen | 2023.8.16 | Micromolecule | |
Zokinvy |
1.00 | Hutchinson-Gilford | EigerBioPharmaceuticals | 2020.11.20 | Micromolecule | |
| Danyelza | 1.00 | Refractory neuroblastoma in bone or bone marrow | Y-mAbs Therapeutics | 2020.11.25 | McAb(monoclonal antibody) | |
