Application of Palmitoylethanolamide（CAS: 544-31-0）produced by Wuxi Further Pharmaceutical in the field of health
Palmitoylethanolamide, commonly known as palmitoylethanolamide (PEA), is an endogenous fatty acid derivative with multiple biological activities, especially in the field of anti-inflammatory and analgesia. The following are its main uses:
1. Medical field
Chronic pain management
PEA has been widely studied for the relief of neuropathic pain (such as diabetic neuropathy, sciatica), fibromyalgia and postoperative pain. It inhibits the release of inflammatory mediators (such as TNF-α, IL-6), regulates mast cell activity, and reduces neuroinflammation.
Adjuvant treatment of neurodegenerative diseases
In diseases such as Alzheimer's disease and multiple sclerosis, PEA may play a potential role by reducing neuroinflammation and protecting neurons.
Immunomodulation
Regulating excessive immune responses may have auxiliary therapeutic effects on autoimmune diseases (such as rheumatoid arthritis).
2. Skin Care
Anti-inflammatory and Soothing
Added to skin care products, relieves inflammatory skin diseases such as eczema, psoriasis, rosacea, and reduces redness, swelling, and irritation.
Barrier Repair
Enhances skin barrier function, reduces water loss, and improves dry and sensitive skin.
3. Animal Health
Pet Joint Health
Used in arthritis supplements for dogs and cats to reduce joint inflammation and pain and improve mobility.
4. Nutritional Supplement
As a dietary supplement, it is used to support the immune system and relieve discomfort associated with chronic inflammation (such as irritable bowel syndrome).
Safety
PEA is well tolerated and has rare side effects (occasionally mild gastrointestinal discomfort), but it must be used under the guidance of professionals, especially when used in combination with drugs.
Summary
With its anti-inflammatory, analgesic, and neuroprotective properties, palmitoylethanolamide (PEA) has important applications in the fields of medicine, skin care, pet health, and nutritional supplements. It is a natural and safe multifunctional compound.
