CAS 98-92-0 Nicotinamide VitaminB3 Nicotinamidum Cosmeitc raw materials

Description:

Nicotinamide aka Vitamin B3 (niacinamide, nicotinic acid amide) is the pyridine 3 carboxylic acid amide form of niacin. It is a water‑soluble vitamin that is not stored in the body. The main source of vitamin in diet is in the form of nicotinamide, nicotinic acid, and tryptophan. The main source of niacin include meat, liver, green leafy vegetables, wheat, oat, palm kernel oil, legumes, yeast, mushrooms, nuts, milk, fish, tea, and coffee.

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Uses:

Nicotinamide is a water-soluble B complex vitamin which is naturally present in animal products, whole cereals and legumes. Together with nicotinic acid (niacin), it belongs to vitamin B3 or vitamin PP, and is required as a nutrient to prevent the niacin deficiency disorder pellagra. It functions as a coenzyme or cosubstrate in many biological reduction and oxidation reactions required for energy metabolism in mammalian systems. It is used as a nutritional supplement, therapeutic agent, skin and hair conditioning agent in cosmetics, and a constituent of consumer household solvent and cleaning products and paints. Nicotinamide is approved for use by the FDA as a food additive to enrich corn meal, farina, rice, and macaroni and noodle products. It is also affirmed as GRAS (Generally Recognized as Safe) by the FDA as a direct human food ingredient which includes its use in infant formula. It is approved for use in pesticide products applied to growing crops only as a synergist with a maximum limitation of 0.5% of formulation.

What are the risks of Nicotinamide?

It might cause side effects such as stomach upset, gas, dizziness, headache, and rash. When applied to the skin: Niacinamide is possibly safe. Niacinamide cream might cause mild burning, itching,or redness. 

What is the difference between vitamin B3 and nicotinamide?

Niacin(also known as vitaminB 3) is one of the water -soluble B vitamins. Niacin is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside [1-3].

What is vitamin B3 nicotinamide good for?

Niacin, also known as vitamin B3, is an important nutrient. In fact, every part of your body needs it to function properly. As a supplement, niacin may help lower cholesterol, ease arthritis, and boost brain function, among other benefits. However, it can also cause serious side effects if you take large doses.
 

niacinamide safe to take daily?

Can you use niacinamide every day? Yes. In fact, you can use niacinamide-containing topical products in the morning and night because it's generally a gentle ingredient.

Can niacinamide brighten skin?

In the clinical studies, niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use. Conclusions: The data suggest niacinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes.
 

Is vitamin B3 good for anti-aging?

Summary. When it comes to anti-aging, vitamin B3 is a key player. This water-soluble vitamin helps to protect cells from damage, supports the production of energy, and reduces inflammation. These benefits work together to help improve overall health and reduce the risk of developing age-related diseases.
 

Why can't you use vitamin C and niacinamide together?

Here's where things get hairy: Older research has shown that mixing vitamin C—specifically the unstable ascorbic acid—with niacinamide can convert it to the compound niacin, which can cause flushing (think blotchy, inflamed skin).

When is the best time to take niacinamide?

Adults and children older than 16 years of age—At first, 500 milligrams (mg) per day, taken at bedtime. After 4 weeks, your doctor will increase your dose to 1000 mg per day, taken at bedtime.

References:

https://www.webmd.com

https://ods.od.nih.gov

https://www.healthline.com

https://chemicalbook.com

https://www.everydayhealth.com

https://pubmed.ncbi.nlm.nih.gov

https://www.healthycell.com

https://www.mindbodygreen.com

https://www.mayoclinic.org