P-Coumaric acid CAS 501-98-4 Trans-4-Coumaric acid Herbal extract Food additive Pharmaceutical inter
P-Coumaric acid |
CAS No.: 501-98-4 |
Purity:>98% |
Molecular weight: 164.16 |
Molecular formula: C9H8O3 |
Appearance:White powder or white needle-shaped crystals |
Package: 1g,10g,100g,1000g |
P-Coumaric acid CAS 501-98-4 Trans-4-Coumaric acid Herbal extract Food additive Pharmaceutical inter
Form:Off-white to beige powder
MW:164.16
Solubility:ethanol: soluble50mg/mL
Synonym:TRANS-4-COUMARIC ACID;
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P-Coumaric acid CAS 501-98-4 Trans-4-Coumaric acid Herbal extract Food additive Pharmaceutical intermediate Antioxidant
Preparation
Synthesis of p-Coumaric acid: take o-acetylsalicyloyl chloride as raw material, in the presence of magnesium chloride, react with diethyl malonate in acetonitrile solvent, then add triethylamine, and react at 0°C for 1 h to obtain ( 2-acetoxybenzoyl) diethyl malonate product, then heated to 50°C in potassium hydroxide/methanol solution, reacted for 3h, and cyclized to obtain p-Coumaric acid.
Uses
Tans-p-Coumaric Acid is the E-isomer of p-Coumaric Acid (C755365), a hydroxy derivative of Cinnamic Acid with antioxidant properties. p-Coumaric acid is a is a major component of lignocellulose. Stud ies suggest that p-Coumaric Acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines.
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