Nicotinamide CAS 98-92-0 Food additives Vitamin Ingredient Cosmetics powder Nicotinamidum White powder odorlessDescription:Nicotinamide aka Vitamin B3 (niacinamide, nicotinic acid amide) is the pyridine 3 carboxylic acid amide form of niacin. It is a water‑soluble vitamin that is not stored in the body. The main source of vitamin in diet is in the form of nicotinamide, nicotinic acid, and tryptophan. The main source of niacin include meat, liver, green leafy vegetables, wheat, oat, palm kernel oil, legumes, yeast, mushrooms, nuts, milk, fish, tea, and coffee.Basic parameters:

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Uses:

Nicotinamide is a water-soluble B complex vitamin which is naturally present in animal products, whole cereals and legumes. Together with nicotinic acid (niacin), it belongs to vitamin B3 or vitamin PP, and is required as a nutrient to prevent the niacin deficiency disorder pellagra. It functions as a coenzyme or cosubstrate in many biological reduction and oxidation reactions required for energy metabolism in mammalian systems. It is used as a nutritional supplement, therapeutic agent, skin and hair conditioning agent in cosmetics, and a constituent of consumer household solvent and cleaning products and paints. Nicotinamide is approved for use by the FDA as a food additive to enrich corn meal, farina, rice, and macaroni and noodle products. It is also affirmed as GRAS (Generally Recognized as Safe) by the FDA as a direct human food ingredient which includes its use in infant formula. It is approved for use in pesticide products applied to growing crops only as a synergist with a maximum limitation of 0.5% of formulation.

Safety:

Nicotinamide is a safe and inexpensive compound with negligible side effects. It is well tolerated even in doses of 1g/day to 3g/day.There are no reports of teratogenicity with nicotinamide. Minor side effects include nausea, vomiting, headache, fatigue. It does not cause vasodilatory side effects like flushing, alteration in blood pressure, body temperature or pulse as seen with niacin.In topical formulation, it does not cause skin irritation, photosensitization in concentrations of 0.0001% to 4%.

What is the difference between vitamin B3 and nicotinamide?

Niacin (also known as vitamin B3) is one of the water-soluble B vitamins. Niacin is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside [1-3]. 

Is vitamin B3 niacinamide good for skin?

Niacinamide (vitamin B3) can help improve the skin's protective barrier by stimulating the synthesis of ceramides within the skin. Ceramides are important components of the skin and help maintain strong bonds between the cells to help strengthen the natural skin barrier.

Is B3 good for anti-aging?

Summary. When it comes to anti-aging, vitamin B3 is a key player. This water-soluble vitamin helps to protect cells from damage, supports the production of energy, and reduces inflammation. These benefits work together to help improve overall health and reduce the risk of developing age-related diseases.

What are the side effects of vitamin B3 nicotinamide?

Side effects may include diarrhea, headache, stomach discomfort, and bloating. High doses (50 mg or more) of niacin can cause side effects. The most common side effect is called "niacin flush," which is a burning, tingling sensation in the face and chest, and red or flushed skin.

Is vitamin B3 good for skin whitening?

Niacinamide (aka nicotinamide) is a water-soluble form of vitamin B3 best known for its multiple skincare benefits. As a skincare ingredient has potent anti-inflammatory, anti-acne, skin brightening, and anti-aging properties. And, it does all this without irritating the skin at all.

References:https://ods.od.nih.govwww.chemicalbook.comhttps://www.cerave.com.auhttps://www.healthycell.comhttps://www.mountsinai.orghttps://www.nume-lab.comChemica book www.chemicalbook.com